July 19, 2019

World-first gene therapy reverses Alzheimer’s memory loss in mice

A ground-breaking new treatment developed by Macquarie University scientists has reversed the effects of memory loss associated with Alzheimer’s disease in a study of mice with advanced dementia.
July 11, 2019

Keys to happiness and longevity

“You can have more purpose — and greater happiness — in the second half of your life.”This quote comes from author Dan Buettner, author of “The Blue Zones of Happiness” and “The Blue Zones: Nine Lessons for Living Longer.”
June 19, 2019

Healthy aging Youthful skin

As people age, they experience change, some pleasant like greater wisdom garnered and some not so fun like crow’s feet and sagging skin. People may be vain, and that’s OK. Or they may be proactive with their personal care and appearance.
May 11, 2019

Difference between NR and NMN

NMN vs NR: both are precursors to NAD, one of nature's most essential molecules for human life, well-being and longevity. It's great that we have such precursors to NAD, because the levels of this essential coenzyme steadily declines as we age.
April 5, 2019

Testing drug combinations to slow aging

The inter-drug relationship of these three drugs can easily be perceived by explicitly defining the mechanism of action of each drug and how it overlaps and extends the mechanism of action of each of the other drugs in the complex.
March 25, 2019

The foods proven to prevent cardiovascular disease and boost longevity

HOW TO live longer: Long life expectancy has a lot to do with the foods we eat and certain diets. This does not mean one should deprive themselves of delicious options. According to studies, filling your plate with more of a certain type of food will reduce the risk of cancer, protect against cardiovascular problems, help with ageing and boost longevity.
February 19, 2019

How important NAD+ is

NAD+ (Nicotinamide adenine dinucleotide) is a cofactor that is central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups.
January 24, 2019

Genetic Diseases

Genetic diseases are any disease caused by an abnormality in the genetic makeup of an individual. The genetic abnormality can range from minuscule to major -- from a discrete mutation in a single base in the DNA of a single gene to a gross chromosomal abnormality involving the addition or subtraction of an entire chromosome or set of chromosomes.
December 17, 2018

SIRT2 Inhibition Ameliorates Cognitive Decline in Mice with Alzheimer’s

A group of scientists have shown that the SIRT2 protein increases the accumulation of amyloid beta, a known marker of Alzheimer’s disease (AD), in the brains of mice. They propose a mechanism underlying this phenomenon and demonstrate that inhibiting SIRT2 ameliorates AD-associated cognitive decline in mice