{"id":28347,"date":"2026-07-22T06:58:57","date_gmt":"2026-07-22T10:58:57","guid":{"rendered":"https:\/\/www.celfull.com\/celfavor-nmnh-2"},"modified":"2026-08-24T03:35:26","modified_gmt":"2026-08-24T07:35:26","slug":"celfavor-nmnh-2","status":"publish","type":"page","link":"https:\/\/www.celfull.com\/es\/celfavor-nmnh-2","title":{"rendered":"Celfavor NMNH"},"content":{"rendered":"\t\t
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<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Celfavor\u00ae MNMH<\/span><\/h1>\n

Mononucle\u00f3tido<\/span>\nde nicotinamida reducido<\/span><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Principales ventajas del producto<\/h2>\r\n \r\n \r\n \"divider\"\r\n\r\n
    \r\n
  • \r\n <\/span>\r\n Como forma reducida del NMN y precursor del NAD+, el NMNH se estudia por su capacidad para aumentar los niveles celulares de NAD+ y NADH, as\u00ed como por sus posibles efectos sobre la funci\u00f3n mitocondrial, la respuesta al estr\u00e9s oxidativo, la reparaci\u00f3n del ADN y el metabolismo. Estas propiedades se investigan por su posible relaci\u00f3n con la fatiga y los procesos biol\u00f3gicos asociados al envejecimiento. <\/span>\r\n <\/li>\r\n
  • \r\n <\/span>\r\n Celfavor\u00ae NMNH utiliza tecnolog\u00eda de encapsulaci\u00f3n en microesferas dise\u00f1ada para estabilizar su actividad y abordar la f\u00e1cil degradaci\u00f3n, la descomposici\u00f3n en el medio \u00e1cido g\u00e1strico y la baja absorci\u00f3n del NMNH. Seg\u00fan los datos experimentales presentados, esta formulaci\u00f3n favorece el aumento de los niveles de NAD+ y se investiga por sus posibles efectos sobre el metabolismo y los procesos relacionados con el envejecimiento.<\/span>\r\n <\/li>\r\n <\/ul>\r\n<\/div>\r\n\r\n\r\n\r\n.adv-title {\r\n font-size: 42px;\r\n color: #004c99;\r\n margin: 0 0 8px 0;\r\n font-weight: bold;\r\n line-height: 1.2;\r\n}\r\n.adv-divider {\r\n display: block;\r\n max-width: 520px;\r\n width: 100%;\r\n margin: 0 0 24px 0;\r\n}\r\n.adv-list {\r\n list-style: none;\r\n padding: 0;\r\n margin: 0;\r\n}\r\n.adv-item {\r\n display: flex;\r\n gap: 14px;\r\n margin-bottom: 26px;\r\n}\r\n.blue-dot {\r\n width: 16px;\r\n height: 16px;\r\n background-color: #004c99;\r\n border-radius: 50%;\r\n flex: 0 0 16px;\r\n margin-top: 8px;\r\n}\r\n.adv-text {\r\n font-size: 18px;\r\n line-height: 1.6;\r\n color: #333;\r\n}\r\n\r\n\/* ===== \u624b\u673a\u7aef\u9002\u914d\uff08767px\u4ee5\u4e0b\uff09===== *\/\r\n@media (max-width:767px){\r\n .adv-title {\r\n font-size: 30px;\r\n }\r\n .adv-text {\r\n font-size: 16px;\r\n }\r\n .adv-item {\r\n gap: 12px;\r\n margin-bottom: 20px;\r\n }\r\n .blue-dot {\r\n width: 14px;\r\n height: 14px;\r\n flex: 0 0 14px;\r\n }\r\n .adv-divider {\r\n max-width: 100%;\r\n }\r\n}\r\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Limitations of Conventional NMNH<\/h2>

    Core Product Advantages<\/h2><\/div>
    \u2716<\/span>

    Unstable<\/h3><\/div>

    Ordinary NMNH has highly unstable chemical properties and is easily oxidized and degraded by light, temperature, humidity, air contact and gastric acid, greatly limiting its wide application.<\/p><\/div>

    \u2713<\/span>

    High stability<\/h3><\/div>

    Celfavor's patented microsphere technology significantly improves the stability of active ingredients, enabling storage for 36 months at room temperature in the dark without degradation in gastric acid.<\/p><\/div><\/div>

    \u2716<\/span>

    Extremely low bioavailability<\/h3><\/div>

    Easily degraded during room-temperature storage and in the gastric acid environment, unable to reach the intestinal tract for absorption.<\/p><\/div>

    \u2713<\/span>

    High bioavailability<\/h3><\/div>

    100% stable retention in the stomach, targeted intestinal release; sustained release in the intestine, greatly improving absorption efficiency.<\/p><\/div><\/div>

    <\/div><\/div>
    \u2713<\/span>

    Stable compounding<\/h3><\/div>

    Suitable for hard capsules, can be compounded with other ingredients<\/p><\/div><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Basic Product Information<\/h2>\"divider\"
    Item<\/th>Details<\/th><\/tr>
    Appearance<\/td>Light yellow microspheres
    (color customizable upon request)<\/td><\/tr>
    NMNH content<\/td>10%<\/td><\/tr>
    Dosage form<\/td>Capsule<\/td><\/tr>
    Recommended dosage<\/td>10\u201320 mg\/day
    (based on NMNH content)<\/td><\/tr><\/table><\/div>.product-info-wrap {\r\n width:100%;\r\n}\r\n.info-title {\r\n font-size:42px;\r\n color:#004c99;\r\n margin:0 0 8px;\r\n font-weight:bold;\r\n line-height:1.2;\r\n}\r\n.info-divider {\r\n display:block;\r\n max-width:540px;\r\n width:100%;\r\n margin:0 0 24px 0;\r\n}\r\n.info-table {\r\n width:100%;\r\n border-collapse: collapse;\r\n font-size:20px;\r\n color:#333;\r\n}\r\n.info-table th,\r\n.info-table td {\r\n border:1px solid #999;\r\n padding:22px 26px;\r\n vertical-align: middle;\r\n line-height:1.5;\r\n}\r\n.info-table th {\r\n background:#f4f4f4;\r\n text-align:left;\r\n font-weight:bold;\r\n}\r\n.info-table td:first-child {\r\n width:36%;\r\n background:#f4f4f4;\r\n font-weight:500;\r\n}\r\n\r\n\/* \u79fb\u52a8\u7aef\u9002\u914d 767px\u4ee5\u4e0b *\/\r\n@media (max-width:767px){\r\n .info-title {\r\n font-size:30px;\r\n }\r\n .info-table {\r\n font-size:16px;\r\n }\r\n .info-table th,\r\n .info-table td {\r\n padding:16px 18px;\r\n }\r\n .info-table td:first-child {\r\n width:42%;\r\n }\r\n .info-divider {\r\n max-width:100%;\r\n }\r\n}\r\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Principales efectos estudiados<\/h2>\r\n \r\n \"divider\"\r\n\r\n
    \r\n
    \r\n 1<\/span>\r\n
    \r\n Aumento eficiente del NAD+:<\/strong>\r\nComo nuevo precursor del NAD+, el NMNH se estudia por su capacidad para aumentar los niveles intracelulares de NAD+ y NADH. Los datos experimentales presentados indican un aumento m\u00e1s r\u00e1pido que el observado con NMN.<\/span>\r\n <\/div>\r\n <\/div>\r\n
    \r\n 2<\/span>\r\n
    \r\n Mejora de la funci\u00f3n mitocondrial:<\/strong>\r\nEn modelos experimentales, se observ\u00f3 un aumento de la expresi\u00f3n del factor de transcripci\u00f3n mitocondrial Tfam, junto con efectos sobre la funci\u00f3n de la cadena de transporte de electrones y el metabolismo energ\u00e9tico mitocondrial.\r\n <\/div>\r\n <\/div>\r\n
    \r\n 3<\/span>\r\n
    \r\n Refuerzo de la capacidad antioxidante:<\/strong>\r\nEn modelos experimentales, se observ\u00f3 un aumento de la expresi\u00f3n del ARNm de enzimas antioxidantes, incluida la glutati\u00f3n peroxidasa, lo que podr\u00eda contribuir a reforzar las defensas antioxidantes celulares.<\/span>\r\n <\/div>\r\n <\/div>\r\n
    \r\n 4<\/span>\r\n
    \r\n Apoyo a la proliferaci\u00f3n y reparaci\u00f3n celular:<\/strong>\r\nEn modelos experimentales, se observ\u00f3 la entrada de las c\u00e9lulas desde la fase G1 hasta la fase S, junto con posibles efectos sobre la capacidad de reparaci\u00f3n celular y tisular.<\/span>\r\n <\/div>\r\n <\/div>\r\n \r\n <\/div>\r\n<\/div>\r\n\r\n\r\n.efficacy-wrap {\r\n width: 100%;\r\n}\r\n.efficacy-title {\r\n font-size: 42px;\r\n color: #004c99;\r\n margin: 0 0 8px;\r\n font-weight: bold;\r\n line-height: 1.2;\r\n}\r\n.efficacy-divider {\r\n display: block;\r\n max-width: 540px;\r\n width: 100%;\r\n margin: 0 0 26px 0;\r\n}\r\n.efficacy-list {\r\n display: flex;\r\n flex-direction: column;\r\n gap: 24px;\r\n}\r\n.efficacy-item {\r\n display: flex;\r\n gap: 14px;\r\n}\r\n.num-mark {\r\n font-size: 26px;\r\n color: #004c99;\r\n font-weight: bold;\r\n flex: 0 0 32px;\r\n line-height: 1.4;\r\n}\r\n.item-content {\r\n font-size: 20px;\r\n line-height: 1.55;\r\n color: #333;\r\n}\r\n.item-head {\r\n color: #004c99;\r\n font-weight: bold;\r\n}\r\n\r\n\/* \u79fb\u52a8\u7aef\u9002\u914d *\/\r\n@media (max-width:767px){\r\n .efficacy-title {\r\n font-size: 30px;\r\n }\r\n .item-content {\r\n font-size: 16px;\r\n }\r\n .num-mark {\r\n font-size: 22px;\r\n flex: 0 0 26px;\r\n }\r\n .efficacy-list {\r\n gap: 18px;\r\n }\r\n .efficacy-divider {\r\n max-width: 100%;\r\n }\r\n}\r\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    Datos experimentales\r\n<\/h2>\r\n \r\n \r\n \"divider\"\r\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    \"\"<\/figure>

    Excelente estabilidad durante la digesti\u00f3n en \u00e1cido g\u00e1strico simulado con pH 2,0<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    \"\"<\/figure>

    Excelente estabilidad en condiciones aceleradas (37 \u00b0C y 75 % de humedad)\n<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    Ratones C57BL\/6 machos de 20 g de peso se asignaron aleatoriamente a cuatro grupos y recibieron por v\u00eda intrag\u00e1strica soluci\u00f3n salina normal, NMN, NMNH o Celfavor\u00ae NMNH, respectivamente, a una dosis de 250 mg\/kg.
    Se recogieron muestras de sangre de la vena safena lateral a las 2, 4 y 20 horas de la primera administraci\u00f3n intrag\u00e1strica. Veinte horas despu\u00e9s se administr\u00f3 una segunda dosis. Cuatro horas despu\u00e9s de esta segunda administraci\u00f3n, los ratones se sometieron a eutanasia bajo anestesia con isoflurano. Se recogieron muestras de sangre y c\u00e9lulas epiteliales de los t\u00fabulos renales, que se congelaron inmediatamente en nitr\u00f3geno l\u00edquido. <\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    \"\"<\/figure>

    Eficacia de Celfavor\u00ae NMNH para aumentar los niveles de NAD+<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    \"\"<\/figure>

    Mejora de la funci\u00f3n mitocondrial (aumento de la expresi\u00f3n del factor de transcripci\u00f3n mitocondrial Tfam)<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    \n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    Celfavor\u00ae MNMH Mononucle\u00f3tido de nicotinamida reducido Principales ventajas del producto Como forma reducida del NMN y precursor del NAD+, el NMNH se estudia por su capacidad para aumentar los niveles celulares de NAD+ y NADH, as\u00ed como por sus posibles efectos sobre la funci\u00f3n mitocondrial, la respuesta al estr\u00e9s oxidativo, la reparaci\u00f3n del ADN y […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_angie_page":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-28347","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/pages\/28347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/comments?post=28347"}],"version-history":[{"count":4,"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/pages\/28347\/revisions"}],"predecessor-version":[{"id":28850,"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/pages\/28347\/revisions\/28850"}],"wp:attachment":[{"href":"https:\/\/www.celfull.com\/es\/wp-json\/wp\/v2\/media?parent=28347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}