{"id":29218,"date":"2026-07-02T05:16:18","date_gmt":"2026-07-02T09:16:18","guid":{"rendered":"https:\/\/www.celfull.com\/related-cases-nmn-2"},"modified":"2026-09-04T03:39:30","modified_gmt":"2026-09-04T07:39:30","slug":"related-cases-nmn","status":"publish","type":"page","link":"https:\/\/www.celfull.com\/zh-hant\/related-cases-nmn","title":{"rendered":"NMN\u76f8\u95dc\u6848\u4f8b"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"29218\" class=\"elementor elementor-29218 elementor-26885\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-210c465 e-flex e-con-boxed e-con e-parent\" data-id=\"210c465\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-db5fa0f elementor-widget elementor-widget-shortcode\" data-id=\"db5fa0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-864d148 e-flex e-con-boxed e-con e-parent\" data-id=\"864d148\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6cb8129 elementor-widget elementor-widget-heading\" data-id=\"6cb8129\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">NMN \u7d50\u5408\u904b\u52d5\u5c0d\u4e2d\u5e74\u53ca\u9577\u8005\u7684\u5f71\u97ff<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec3286d e-flex e-con-boxed e-con e-parent\" data-id=\"ec3286d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c18b403 e-con-full e-flex e-con e-child\" data-id=\"c18b403\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-14e7418 elementor-widget elementor-widget-text-editor\" data-id=\"14e7418\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>\u7814\u7a76\u767c\u73fe\uff1a<\/h3><div class=\"ytable\"><div class=\"ytable-cell txt\"><p>\u672c\u7814\u7a76\u63a1\u7528\u5b89\u6170\u5291\u5c0d\u7167\u3001\u96d9\u76f2\u81e8\u5e8a\u8a66\u9a57\uff0c\u8a55\u4f30 NMN \u8207\u5e36\u6c27\u904b\u52d5\u5e36\u4f86\u7684\u6548\u679c\u3002\u7d50\u679c\u986f\u793a\uff0c\u9023\u7e8c 30 \u65e5\u53e3\u670d NMN \u88dc\u5145\u5291\uff08\u6bcf\u65e5 500 \u6beb\u514b\u6216 1000 \u6beb\u514b\uff09\uff0c\u80fd\u5920\u4ee5\u5291\u91cf\u4f9d\u8cf4\u5f62\u5f0f\u986f\u8457\u63d0\u5347\u5168\u8840 NAD + \u6c34\u5e73\uff1b\u800c\u5e36\u6c27\u904b\u52d5\u53ef\u9032\u4e00\u6b65\u63d0\u5347\u5c0d\u7167\u7d44\u53ca NMN \u8655\u7406\u7d44\u7684 NAD + \u6c34\u5e73\u3002 <\/p><p>\u5728\u6bcf\u65e5 1000 \u6beb\u514b NMN \u8655\u7406\u7d44\u7576\u4e2d\uff0c\u90e8\u5206\u53d7\u8a66\u8005\u5c0d NMN \u88dc\u5145\u4e26\u7121\u53cd\u61c9\u3002\u5176\u5f8c\uff0c\u6211\u5011\u5c0d\u8a72\u7d44 4 \u540d\u6709\u53cd\u61c9\u53ca\u7121\u53cd\u61c9\u53d7\u8a66\u8005\u7684\u5468\u908a\u8840\u55ae\u6838\u7d30\u80de\uff08PBMCs\uff09\u9032\u884c\u5927\u898f\u6a21 RNA \u6e2c\u5e8f\uff0c\u5206\u6790\u53c3\u8207 NAD + \u4ee3\u8b1d\u7684\u57fa\u56e0\u8868\u9054\u6c34\u5e73\u3002\u6709\u53cd\u61c9\u4eba\u58eb\u9ad4\u5167\uff0cIDO2\u3001NAPRT\u3001NMNAT2\u3001NAMPT \u7b49 NAD + \u5408\u6210\u9176\uff0c\u4ee5\u53ca\u6838\u82f7\u8f49\u904b\u86cb\u767d SLC29A3 \u8868\u9054\u91cf\u8f03\u9ad8\uff1b\u800c\u7121\u53cd\u61c9\u4eba\u58eb\u5247\u6709\u8f03\u9ad8\u7684 SIRT4\u3001PARP14\u3001CD38\u3001PARP2 \u7b49 NAD + \u6d88\u8017\u9176\u8868\u9054\u3002  <\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dc449dc e-con-full e-flex e-con e-child\" data-id=\"dc449dc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-604dc3e elementor-widget elementor-widget-image\" data-id=\"604dc3e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"480\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/1-241029141501D2.jpg\" class=\"attachment-large size-large wp-image-29204\" alt=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/1-241029141501D2.jpg 800w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/1-241029141501D2-300x180.jpg 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/1-241029141501D2-768x461.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a71cf8b e-flex e-con-boxed e-con e-parent\" data-id=\"a71cf8b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-6294af7 e-con-full e-flex e-con e-child\" data-id=\"6294af7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d9147d2 elementor-widget elementor-widget-image\" data-id=\"d9147d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"760\" height=\"280\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img1.png\" class=\"attachment-large size-large wp-image-29219\" alt=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img1.png 760w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img1-300x111.png 300w\" sizes=\"(max-width: 760px) 100vw, 760px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-be21761 e-con-full e-flex e-con e-child\" data-id=\"be21761\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8c34e44 elementor-widget elementor-widget-text-editor\" data-id=\"8c34e44\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u8a55\u4f30\u53e3\u670d NMN \u88dc\u5145\u6548\u679c\u4e4b\u7814\u7a76\u8a2d\u8a08\u3002\u9023\u7e8c 1 \u500b\u6708\u6bcf\u65e5\u88dc\u5145 500 \u6beb\u514b\uff08n=19\uff09\u53ca 1000 \u6beb\u514b NMN\uff08n=22\uff09\uff0c\u76f8\u8f03\u5b89\u6170\u5291\u7d44\uff08n=25\uff09\u53ef\u986f\u8457\u63d0\u5347\u975c\u8108\u8840 NAD + \u6fc3\u5ea6\u3002\u8aa4\u5dee\u68d2\u4ee3\u8868\u5404\u7d44 SD\u3002\u7d71\u8a08\u986f\u8457\u6027\u900f\u904e\u55ae\u5411 ANOVA \u5206\u6790\u5f97\u51fa\uff0c* p&lt; 0.05\u3001** p&lt; 0.01\u3001*** p&lt; 0.001\u3001**** p &lt;0.0001\u3002   <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9f364e7 e-flex e-con-boxed e-con e-parent\" data-id=\"9f364e7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c10da65 e-con-full e-flex e-con e-child\" data-id=\"c10da65\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f097182 elementor-widget elementor-widget-text-editor\" data-id=\"f097182\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u8a55\u4f30\u53e3\u670d NMN \u88dc\u5145\u914d\u5408\u9069\u91cf\u904b\u52d5\u4e4b\u7814\u7a76\u8a2d\u8a08\u3002\u6bd4\u8f03\u300c\u5e36\u6c27\u904b\u52d5\u642d\u914d\u53e3\u670d NMN \u88dc\u5145\uff08n=20\uff09\u300d\u8207\u300c\u55ae\u7d14\u5e36\u6c27\u904b\u52d5\uff08n=21\uff09\u300d\u5c0d\u975c\u8108\u8840 NAD + \u6c34\u5e73\u7684\u5f71\u97ff\u3002\u8aa4\u5dee\u68d2\u4ee3\u8868\u5404\u7d44 SD\u3002\u7d71\u8a08\u986f\u8457\u6027\u900f\u904e t\u2011test \u5f97\u51fa\uff0c* p&lt; 0.05\u3001** p&lt; 0.01\u3001*** p&lt;0.001\u3001**** p&lt; 0.0001\u3002   <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1b7e762 e-con-full e-flex e-con e-child\" data-id=\"1b7e762\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b759be1 elementor-widget elementor-widget-image\" data-id=\"b759be1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"792\" height=\"305\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img2.png\" class=\"attachment-large size-large wp-image-29220\" alt=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img2.png 792w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img2-300x116.png 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/NMN-img2-768x296.png 768w\" sizes=\"(max-width: 792px) 100vw, 792px\" title=\"\">\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bd646f6 e-flex e-con-boxed e-con e-parent\" data-id=\"bd646f6\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b5ee68 elementor-widget elementor-widget-text-editor\" data-id=\"2b5ee68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u5c0d NMN \u88dc\u5145\u6709\u53cd\u61c9\u53ca\u7121\u53cd\u61c9\u53d7\u8a66\u8005\u4e4b NAD + \u4ee3\u8b1d\u76f8\u95dc\u57fa\u56e0\u76f8\u5c0d\u8868\u9054\u91cf\u3002(a) \u9023\u7e8c 30 \u65e5\u6bcf\u65e5 1000 \u6beb\u514b NMN \u88dc\u5145\u5f8c\uff0cNMN \u6709\u53cd\u61c9\u53ca\u7121\u53cd\u61c9\u53d7\u8a66\u8005\u7684\u5168\u8840 NAD + \u6c34\u5e73\u6e2c\u91cf\u7d50\u679c\u3002(b) \u4f9d\u64da NAD + \u6e2c\u91cf\u7d50\u679c\uff0c\u65bc\u81e8\u5e8a\u7814\u7a76\u5b8c\u7d50\u5f8c\uff0c\u62bd\u53d6 4 \u540d\u5c0d NMN \u5206\u5225\u6709\u53cd\u61c9\u53ca\u7121\u53cd\u61c9\u53d7\u8a66\u8005\u7684\u975c\u8108\u8840\u5206\u96e2 PBMCs \u4e26\u9032\u884c\u6e2c\u5e8f\uff0c\u5f97\u5230 NAD + \u4ee3\u8b1d\u76f8\u95dc\u57fa\u56e0\u8868\u9054\u8b5c\u3002\u8aa4\u5dee\u68d2\u4ee3\u8868 SD\uff1b(a) \u90e8\u5206\u7d71\u8a08\u986f\u8457\u6027\u900f\u904e t\u2011test \u8a08\u7b97\uff0c**** p&lt; 0.0001\u3002    <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>NMN \u7d50\u5408\u904b\u52d5\u5c0d\u4e2d\u5e74\u53ca\u9577\u8005\u7684\u5f71\u97ff \u7814\u7a76\u767c\u73fe\uff1a \u672c\u7814\u7a76\u63a1\u7528\u5b89\u6170\u5291\u5c0d\u7167\u3001\u96d9\u76f2\u81e8\u5e8a\u8a66\u9a57\uff0c\u8a55\u4f30 NMN \u8207\u5e36\u6c27\u904b\u52d5\u5e36 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-29218","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/pages\/29218","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=29218"}],"version-history":[{"count":5,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/pages\/29218\/revisions"}],"predecessor-version":[{"id":29408,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/pages\/29218\/revisions\/29408"}],"wp:attachment":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=29218"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}