{"id":29714,"date":"2026-03-20T11:38:00","date_gmt":"2026-03-20T15:38:00","guid":{"rendered":"https:\/\/www.celfull.com\/%e6%9c%aa%e5%88%86%e9%a1%9e\/nadh-nad-ratio-determines-brain-aging-speed-the-truth-about-fasting-keto-anti-aging.html"},"modified":"2026-09-18T04:31:56","modified_gmt":"2026-09-18T08:31:56","slug":"nadh-nad-ratio-determines-brain-aging-speed-the-truth-about-fasting-keto-anti-aging","status":"publish","type":"post","link":"https:\/\/www.celfull.com\/zh-hant\/%e6%96%b0%e8%81%9e\/nadh-nad-ratio-determines-brain-aging-speed-the-truth-about-fasting-keto-anti-aging.html","title":{"rendered":"NADH\/NAD+ \u6bd4\u503c\uff1a2026 \u5e74\u79d1\u5b78\u63ed\u793a\u5927\u8166\u8870\u8001\u8207\u65b7\u98df\u3001\u751f\u916e\u7684\u771f\u76f8"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">NADH\/NAD+ \u6bd4\u503c\u662f\u63a7\u5236\u5927\u8166\u8870\u8001\u901f\u5ea6\u3001\u8a8d\u77e5\u8870\u9000\u548c\u795e\u7d93\u5143\u4ee3\u8b1d\u5065\u5eb7\u7684\u6838\u5fc3\u751f\u7269\u958b\u95dc\u3002\u4e00\u9805 2026 \u5e74\u767c\u8868\u65bc Frontiers in Aging Neuroscience \u7684\u958b\u5275\u6027\u7814\u7a76\uff0c\u63ed\u793a\u4e86 NADH\/NAD+ \u6bd4\u503c\u548c NADPH\/NADP+ \u6c27\u5316\u9084\u539f\u5e73\u8861\u5982\u4f55\u5851\u9020\u5927\u8166\u8870\u8001\uff0c\u540c\u6642\u95e1\u660e\u65b7\u98df\u8207\u751f\u916e\u98f2\u98df\u6297\u8870\u8001\u6a5f\u5236\u4e4b\u9593\u7684\u771f\u5be6\u5dee\u7570\uff0c\u5be6\u73fe\u7cbe\u6e96\u7684\u8a8d\u77e5\u4fdd\u8b77\u3002 <\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"820\" height=\"547\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-5.png\" alt=\"\" class=\"wp-image-27205\" title=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-5.png 820w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-5-300x200.png 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-5-768x512.png 768w\" sizes=\"(max-width: 820px) 100vw, 820px\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\">1. \u5927\u8166\u8870\u8001\u6838\u5fc3\u6a5f\u5236\uff1aNADH\/NAD+ \u6bd4\u503c\u5931\u8861\u5982\u4f55\u89f8\u767c\u8a8d\u77e5\u8870\u9000<\/h3>\n\n<p class=\"wp-block-paragraph\">\u4ee5 NADH\/NAD+ \u6bd4\u503c\u70ba\u4e3b\u7684\u7d30\u80de\u6c27\u5316\u9084\u539f\u7a69\u614b\uff0c\u662f\u8166\u7d30\u80de\u4ee3\u8b1d\u6548\u7387\u548c\u6297\u6c27\u5316\u9632\u79a6\u80fd\u529b\u7684\u6839\u672c\u6c7a\u5b9a\u56e0\u7d20\u3002NAD+ \u8207 NADH \u4e4b\u9593\u7684\u76f8\u4e92\u8f49\u5316\u652f\u6301 ATP \u5408\u6210\uff0c\u70ba\u6240\u6709\u795e\u7d93\u5143\u6d3b\u52d5\u63d0\u4f9b\u80fd\u91cf\u3002\u8207\u6b64\u540c\u6642\uff0c\u5b83\u5011\u7684\u78f7\u9178\u5316\u884d\u751f\u7269 NADPH \u548c NADP+ \u627f\u64d4\u6838\u5fc3\u6297\u6c27\u5316\u529f\u80fd\uff0c\u62b5\u6297\u795e\u7d93\u5143\u7684\u6c27\u5316\u58d3\u529b\u548c\u640d\u50b7\u7d2f\u7a4d\u3002  <\/p>\n\n<p class=\"wp-block-paragraph\">\u79d1\u5b78\u7684\u6c27\u5316\u9084\u539f\u8870\u8001\u7406\u8ad6\u8b49\u5be6\uff0c\u5927\u8166\u8870\u8001\u672c\u8cea\u4e0a\u662f\u6c27\u5316\u9084\u539f\u6bd4\u503c\u5931\u8861\u7684\u75c5\u7406\u72c0\u614b\u3002NAD (H) \u7cfb\u7d71\u8abf\u7bc0\u8d85\u904e 300 \u7a2e\u95dc\u9375\u7d30\u80de\u4ee3\u8b1d\u53cd\u61c9\uff0c\u800c NADP (H) \u7cfb\u7d71\u63a7\u5236\u8fd1 100 \u7a2e\u751f\u7406\u904e\u7a0b\u3002\u4e00\u65e6\u5b83\u5011\u7684\u6bd4\u4f8b\u5e73\u8861\u5d29\u6f70\uff0c\u8166\u7d30\u80de\u80fd\u91cf\u4ee3\u8b1d\u7d0a\u4e82\u548c\u6297\u6c27\u5316\u80fd\u529b\u4e0b\u964d\u4fbf\u4e0d\u53ef\u907f\u514d\uff0c\u52a0\u901f\u5927\u8166\u529f\u80fd\u8870\u8001\u3002  <\/p>\n\n<p class=\"wp-block-paragraph\">\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u6c27\u5316\u9084\u539f\u8870\u8001\u6a5f\u5236\u5728\u4e0d\u540c\u7269\u7a2e\u751a\u81f3\u5c0f\u9f20\u54c1\u7cfb\u4e4b\u9593\u5b58\u5728\u986f\u8457\u5dee\u7570\u3002\u5728\u4eba\u985e\u548c C57BL\/6N \u5c0f\u9f20\u4e2d\uff0c\u8166\u7d30\u80de\u8cea NADH\/NAD+ \u6bd4\u503c\u96a8\u5e74\u9f61\u5448\u6c27\u5316\u6027\u504f\u79fb\uff0c\u5c0e\u81f4\u80fd\u91cf\u4f9b\u61c9\u4e0d\u8db3\u548c\u795e\u7d93\u4fdd\u8b77\u6e1b\u5f31\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0cC57BL\/6J \u5c0f\u9f20\u7684\u5927\u8166\u5448\u73fe\u9084\u539f\u6027\u6c27\u5316\u9084\u539f\u504f\u79fb\uff0c\u4e14\u58fd\u547d\u66f4\u9577\uff0c\u5f37\u6709\u529b\u5730\u8b49\u660e\u7cbe\u6e96\u7684\u6c27\u5316\u9084\u539f\u6bd4\u503c\u5e73\u8861\u8207\u5927\u8166\u8870\u8001\u901f\u5ea6\u548c\u9577\u58fd\u76f4\u63a5\u76f8\u95dc\u3002  <\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"865\" height=\"851\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-7.png\" alt=\"\" class=\"wp-image-27207\" title=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-7.png 865w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-7-300x295.png 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-7-768x756.png 768w\" sizes=\"(max-width: 865px) 100vw, 865px\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\">2. \u65b7\u98df vs \u751f\u916e\u98f2\u98df\uff1a\u5404\u81ea\u5982\u4f55\u8abf\u7bc0\u8166\u90e8 NADH\/NAD+ \u6bd4\u503c<\/h3>\n\n<p class=\"wp-block-paragraph\">\u65b7\u98df\u548c\u751f\u916e\u98f2\u98df\u662f\u5169\u7a2e\u4e3b\u6d41\u7684\u98f2\u98df\u6297\u8870\u8001\u65b9\u6cd5\uff0c\u4f46\u5b83\u5011\u8abf\u7bc0\u5927\u8166\u8870\u8001\u7684\u6a5f\u5236\u5b8c\u5168\u4e0d\u540c\uff0c\u539f\u56e0\u6b63\u5728\u65bc\u5b83\u5011\u5c0d NADH\/NAD+ \u6bd4\u503c\u548c NADPH\/NADP+ \u6c27\u5316\u9084\u539f\u5e73\u8861\u7684\u8abf\u7bc0\u65b9\u5f0f\u622a\u7136\u4e0d\u540c\u3002<\/p>\n\n<p class=\"wp-block-paragraph\">\u65b7\u98df\u548c\u9577\u671f\u71b1\u91cf\u9650\u5236\u70ba\u5927\u8166\u5275\u9020\u5168\u8eab\u6027\u7684\u6297\u8870\u8001\u4ee3\u8b1d\u72c0\u614b\u3002\u77ed\u671f\u65b7\u98df\uff083\u201324 \u5c0f\u6642\uff09\u548c\u6301\u7e8c\u71b1\u91cf\u9650\u5236\u90fd\u6703\u5728\u4eba\u985e\u548c\u5c0f\u9f20\u8166\u7d44\u7e54\u4e2d\u8a98\u5c0e\u6eab\u548c\u7684\u9084\u539f\u6027\u504f\u79fb\uff0c\u7a69\u5b9a\u7d30\u80de\u8cea\u548c\u7c92\u7dda\u9ad4\u7684 NADH\/NAD+ \u6bd4\u503c\u53ca NADPH\/NADP+ \u5e73\u8861\u3002\u7336\u5982\u5c0d\u8d85\u8ca0\u8377\u7684\u8166\u7d30\u80de\u9032\u884c\u5b9a\u671f\u7cfb\u7d71\u7dad\u8b77\uff0c\u65b7\u98df\u6fc0\u6d3b AMPK \u548c SIRT \u86cb\u767d\u6297\u8870\u8001\u9014\u5f91\uff0c\u6291\u5236\u904e\u91cf\u8102\u80aa\u9178\u5408\u6210\uff0c\u4fc3\u9032\u8102\u80aa\u9178 \u03b2- \u6c27\u5316\uff0c\u6e1b\u5c11\u7121\u6548\u80fd\u91cf\u6d88\u8017\uff0c\u4e26\u5132\u5099\u5145\u8db3\u7684 NADPH \u6297\u6c27\u5316\u8cc7\u6e90\u3002\u9593\u6b47\u6027\u65b7\u98df\u5f15\u767c\u7684\u9031\u671f\u6027\u6c27\u5316\u9084\u539f\u5207\u63db\uff0c\u4ea6\u80fd\u6709\u6548\u62b5\u6297\u795e\u7d93\u5143\u7c92\u7dda\u9ad4\u8870\u8001\uff0c\u70ba\u5176\u7d93\u5178\u7684\u6297\u8870\u8001\u5730\u4f4d\u5960\u5b9a\u4e86\u5805\u5be6\u7684\u79d1\u5b78\u57fa\u790e\u3002    <\/p>\n\n<p class=\"wp-block-paragraph\">Different from universal fasting regulation, ketogenic diets and ketone ester supplementation present compartment-specific redox regulation and are not suitable for all groups. The keto diet induces an oxidative shift in the cytoplasmic<strong>NADH\/NAD+ ratio<\/strong> in the cerebral cortex and hippocampus, while causing a reductive shift in hippocampal mitochondria. This difference stems from distinct ketone body concentrations: fasting can elevate plasma \u03b2-hydroxybutyrate levels 5\u201320 times, whereas the ketogenic diet only increases them 0.4\u20132 times, leading to different regulatory effects on insulin and glucagon secretion.  <\/p>\n\n<p class=\"wp-block-paragraph\">\u56e0\u6b64\uff0c\u751f\u916e\u98f2\u98df\u53ea\u5c0d\u963f\u8332\u6d77\u9ed8\u75c7\u9ad8\u98a8\u96aa\u4eba\u7fa4\u548c\u6a21\u578b\u5c0f\u9f20\u7b49\u7279\u5b9a\u7fa4\u9ad4\u6709\u6548\uff0c\u800c\u975e\u901a\u7528\u7684\u8166\u90e8\u6297\u8870\u8001\u65b9\u6848\u3002\u76f2\u76ee\u751f\u916e\u53ef\u80fd\u64fe\u4e82\u6574\u9ad4\u5927\u8166\u6c27\u5316\u9084\u539f\u5e73\u8861\uff0c\u7121\u6cd5\u5be6\u73fe\u6297\u8870\u8001\u76ee\u6a19\u3002 <\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"834\" height=\"625\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-6.png\" alt=\"\" class=\"wp-image-27206\" title=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-6.png 834w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-6-300x225.png 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-6-768x576.png 768w\" sizes=\"(max-width: 834px) 100vw, 834px\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\">3. \u661f\u5f62\u81a0\u8cea\u7d30\u80de\uff1a\u7a69\u5b9a NADH\/NAD+ \u6bd4\u503c\uff0c\u5b88\u8b77\u5927\u8166\u7a69\u614b<\/h3>\n\n<p class=\"wp-block-paragraph\">\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u662f\u8166\u5167\u95dc\u9375\u7684\u652f\u6301\u7d30\u80de\uff0c\u662f\u795e\u7d93\u5143\u5065\u5eb7\u548c\u6c27\u5316\u9084\u539f\u5e73\u8861\u7684\u91cd\u8981\u7dad\u8b77\u8005\uff0c\u4e5f\u662f\u7a69\u5b9a\u5927\u8166 NADH\/NAD+ \u6bd4\u503c\u7684\u6838\u5fc3\u9632\u7dda\u3002\u8207\u8106\u5f31\u7684\u795e\u7d93\u5143\u4e0d\u540c\uff0c\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u9069\u5ea6\u8868\u9054\u860b\u679c\u9178\u9176 1\uff08ME1\uff09\u548c\u4e73\u9178\u812b\u6c2b\u9176\uff08LDH\uff09\uff0c\u5f62\u6210\u7d30\u80de\u8cea NADPH\/NADP+ \u8207 NADH\/NAD+ \u6bd4\u503c\u4e4b\u9593\u7684\u53cd\u5411\u8026\u5408\u6a5f\u5236\u3002\u9019\u7a2e\u7368\u7279\u7d50\u69cb\u80fd\u9ad8\u6548\u7a69\u5b9a\u8166\u90e8\u6c27\u5316\u9084\u539f\u72c0\u614b\uff0c\u62b5\u6297\u8870\u8001\u76f8\u95dc\u7684\u6c27\u5316\u58d3\u529b\u3002  <\/p>\n\n<p class=\"wp-block-paragraph\">\u7531\u65bc ME1 \u8868\u9054\u8f03\u4f4e\uff0c\u795e\u7d93\u5143\u66f4\u5bb9\u6613\u53d7\u5230\u6c27\u5316\u9084\u539f\u5931\u8861\u548c\u6c27\u5316\u640d\u50b7\u7684\u5f71\u97ff\uff0c\u6210\u70ba\u5927\u8166\u8870\u8001\u7684\u4e3b\u8981\u53d7\u5bb3\u8005\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u5be6\u9a57\u6578\u64da\u986f\u793a\uff0c18 \u500b\u6708\u9f61\u8870\u8001\u5927\u9f20\u7684\u661f\u5f62\u81a0\u8cea\u7d30\u80de\uff0c\u5176\u7c92\u7dda\u9ad4\u547c\u5438\u80fd\u529b\u6bd4 7 \u500b\u6708\u9f61\u5e74\u8f15\u5927\u9f20\u66f4\u5f37\uff0c\u8ce6\u4e88\u5b83\u5011\u51fa\u8272\u7684\u6297\u8870\u8001\u9069\u61c9\u6027\u3002\u9019\u4e00\u91cd\u8981\u767c\u73fe\u8868\u660e\uff0c\u91dd\u5c0d\u6027\u8abf\u7bc0\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u7684\u4ee3\u8b1d\u7279\u5fb5\u548c\u6c27\u5316\u9084\u539f\u5e73\u8861\uff0c\u5c07\u6210\u70ba\u672a\u4f86\u7cbe\u6e96\u8166\u90e8\u6297\u8870\u8001\u5e72\u9810\u7684\u65b0\u65b9\u5411\u3002  <\/p>\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"832\" height=\"832\" src=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-8.png\" alt=\"\" class=\"wp-image-27208\" title=\"\" srcset=\"https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-8.png 832w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-8-300x300.png 300w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-8-150x150.png 150w, https:\/\/www.celfull.com\/wp-content\/uploads\/2026\/07\/image-8-768x768.png 768w\" sizes=\"(max-width: 832px) 100vw, 832px\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\">4. \u5be6\u7528\u6297\u8870\u8001\u5efa\u8b70\uff1a\u8abf\u6574 NADH\/NAD+ \u6bd4\u503c\uff0c\u7dad\u8b77\u9577\u671f\u5927\u8166\u5065\u5eb7<\/h3>\n\n<p class=\"wp-block-paragraph\">\u8907\u96dc\u7684\u6297\u8870\u8001\u65b9\u6848\u4e26\u975e\u5fc5\u8981\uff1b\u91dd\u5c0d NADH\/NAD+ \u6bd4\u503c\u7684\u65e5\u5e38\u5fae\u8abf\uff0c\u5373\u53ef\u6709\u6548\u5ef6\u7de9\u5927\u8166\u8870\u8001\u4e26\u7dad\u6301\u8a8d\u77e5\u529f\u80fd\u3002<\/p>\n\n<p class=\"wp-block-paragraph\">\u9593\u6b47\u6027\u65b7\u98df\u662f\u6700\u5bb9\u6613\u4e0a\u624b\u4e14\u9ad8\u6548\u7684\u65b9\u6cd5\u3002\u6bcf\u9031\u63a1\u7528 1\u20132 \u6b21\u7d93\u5178\u7684 16:8 \u65b7\u98df\u6cd5\uff0c\u53ef\u5be6\u73fe\u8166\u7d30\u80de\u7684\u898f\u5f8b\u4ee3\u8b1d\u5207\u63db\uff0c\u7a69\u5b9a\u7dad\u6301\u6c27\u5316\u9084\u539f\u5e73\u8861\uff0c\u7121\u9700\u904e\u5ea6\u98f2\u98df\u9650\u5236\u6216\u8eab\u9ad4\u8ca0\u64d4\u3002 <\/p>\n\n<p class=\"wp-block-paragraph\">\u5408\u7406\u7684\u71df\u990a\u88dc\u5145\u6709\u52a9\u65bc\u6c27\u5316\u9084\u539f\u5e73\u8861\u8abf\u7bc0\u3002\u79d1\u5b78\u7684 NADH \u88dc\u5145\u80fd\u77ef\u6b63\u8870\u8001\u8166\u7d30\u80de\u7570\u5e38\u7684\u6c27\u5316\u6027\u6c27\u5316\u9084\u539f\u504f\u79fb\uff0c\u64f4\u5927\u7d30\u80de\u5167 NAD \u4ee3\u8b1d\u5132\u5099\uff0c\u96d9\u91cd\u652f\u6301\u795e\u7d93\u5143\u80fd\u91cf\u7522\u751f\u548c\u6297\u6c27\u5316\u9632\u79a6\u3002\u5929\u7136\u534a\u80f1\u6c28\u9178\uff08\u5bcc\u542b\u65bc\u96de\u86cb\u3001\u7626\u8089\u548c\u8c46\u985e\uff09\u80fd\u6062\u5fa9\u8870\u8001\u795e\u7d93\u5143\u7684\u7c92\u7dda\u9ad4 NADH \u6c34\u5e73\uff0c\u901a\u904e H\u2082S \u4fe1\u865f\u4fdd\u8b77\u7c92\u7dda\u9ad4\u529f\u80fd\uff0c\u9032\u4e00\u6b65\u512a\u5316\u5927\u8166\u7684 NADH\/NAD+ \u6bd4\u503c\u3002  <\/p>\n\n<h3 class=\"wp-block-heading\">5. \u95dc\u9375\u7d50\u8ad6\uff1aNADH\/NAD+ \u6bd4\u503c\u5e73\u8861\u5b9a\u7fa9\u5927\u8166\u8870\u8001\u901f\u5ea6<\/h3>\n\n<p class=\"wp-block-paragraph\">\u9019\u9805 2026 \u5e74\u524d\u6cbf\u7814\u7a76\u985b\u8986\u4e86\u50b3\u7d71\u8a8d\u77e5\uff1a\u5927\u8166\u8870\u8001\u4e26\u975e\u4e0d\u53ef\u9006\u8f49\u7684\u81ea\u7136\u8870\u9000\uff0c\u800c\u662f NADH\/NAD+ \u548c NADPH\/NADP+ \u6c27\u5316\u9084\u539f\u6bd4\u503c\u6301\u7e8c\u5931\u8861\u7684\u75c5\u7406\u72c0\u614b\u3002\u901a\u904e\u65b7\u98df\u9032\u884c\u9031\u671f\u6027\u4ee3\u8b1d\u7dad\u8b77\u3001\u661f\u5f62\u81a0\u8cea\u7d30\u80de\u7684\u5167\u6e90\u6027\u5e73\u8861\u4fdd\u8b77\u3001\u4ee5\u53ca\u91dd\u5c0d\u6027\u71df\u990a\u88dc\u5145\uff0c\u90fd\u80fd\u8abf\u7bc0\u9019\u4e9b\u6838\u5fc3\u7d30\u80de\u300c\u80fd\u91cf\u958b\u95dc\u300d\uff0c\u9006\u8f49\u4e9e\u5065\u5eb7\u8870\u8001\u72c0\u614b\u3002 <\/p>\n\n<p class=\"wp-block-paragraph\">\u9ad8\u6548\u7684\u5927\u8166\u6297\u8870\u8001\u4e0d\u4f9d\u8cf4\u8907\u96dc\u7b56\u7565\u6216\u6602\u8cb4\u7522\u54c1\u3002\u901a\u904e\u79d1\u5b78\u98f2\u98df\u7fd2\u6163\u548c\u9069\u5ea6\u9593\u6b47\u6027\u65b7\u98df\u6301\u7e8c\u7a69\u5b9a\u8166\u90e8\u6c27\u5316\u9084\u539f\u5e73\u8861\uff0c\u662f\u6700\u5b89\u5168\u3001\u6700\u6709\u6548\u7684\u9577\u671f\u8a8d\u77e5\u4fdd\u8b77\u65b9\u6848\u3002\u96a8\u8457\u5c0d\u8166\u90e8\u6c27\u5316\u9084\u539f\u8abf\u7bc0\u7db2\u7d61\u7684\u6df1\u5165\u7814\u7a76\uff0c\u672a\u4f86\u5c07\u958b\u767c\u51fa\u66f4\u7cbe\u6e96\u3001\u66f4\u500b\u4eba\u5316\u7684\u6297\u8870\u8001\u5e72\u9810\uff0c\u70ba\u5ef6\u7de9\u5927\u8166\u8870\u8001\u548c\u4fdd\u8b77\u8a8d\u77e5\u5065\u5eb7\u5e36\u4f86\u65b0\u7a81\u7834\u3002  <\/p>\n\n<p class=\"wp-block-paragraph\">\u5fc5\u9808\u5f37\u8abf\u7684\u662f\uff0c\u5927\u8166\u6297\u8870\u8001\u8ffd\u6c42\u7684\u662f\u6c27\u5316\u9084\u539f\u5e73\u8861\uff0c\u800c\u975e\u55ae\u4e00\u7269\u8cea\u7684\u904e\u5ea6\u88dc\u5145\u3002\u904e\u91cf\u651d\u5165 NADPH \u6216\u76f8\u95dc\u71df\u990a\u7d20\u6703\u89f8\u767c\u767c\u708e\u53cd\u61c9\u4e26\u7834\u58de\u4ee3\u8b1d\u7a69\u5b9a\uff0c\u53cd\u800c\u52a0\u901f\u8870\u8001\u3002\u61c9\u512a\u5148\u63a1\u53d6\u591a\u6a23\u5316\u7684\u5929\u7136\u98f2\u98df\u651d\u5165\uff0c\u4ee5\u512a\u8cea\u88dc\u5145\u54c1\u4f5c\u70ba\u8f14\u52a9\u8abf\u7bc0\u3002  <br\/><\/p>\n\n<p class=\"wp-block-paragraph\">\u53c3\u8003\u6587\u737b<br\/><strong>amerson L E, Bradshaw T D, Bradshaw P C. Changes in the brain [NAD+]\/[NADH] and [NADPH]\/[NADP+] with aging and anti-aging dietary restriction[J]. Frontiers in Aging Neuroscience, 2026, 18: 1689139.<\/strong><\/p>\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NADH\/NAD+ \u6bd4\u503c\u662f\u63a7\u5236\u5927\u8166\u8870\u8001\u901f\u5ea6\u3001\u8a8d\u77e5\u8870\u9000\u548c\u795e\u7d93\u5143\u4ee3\u8b1d\u5065\u5eb7\u7684\u6838\u5fc3\u751f\u7269\u958b\u95dc\u3002\u4e00\u9805 2026 \u5e74\u767c\u8868\u65bc  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":29715,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"page_builder":"","footnotes":""},"categories":[95],"tags":[],"class_list":["post-29714","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-95"],"_links":{"self":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/posts\/29714","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=29714"}],"version-history":[{"count":1,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/posts\/29714\/revisions"}],"predecessor-version":[{"id":29716,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/posts\/29714\/revisions\/29716"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/media\/29715"}],"wp:attachment":[{"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=29714"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=29714"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.celfull.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=29714"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}