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Nature Metabolism: Mitochondrial NAD+ Homeostasis Regulates Liver Regeneration

NAD+ is an indispensable core coenzyme that dominates cellular redox reactions, energy metabolism, and signal transduction. Its metabolic imbalance is closely linked to multiple chronic diseases and organ dysfunction. While numerous studies have verified that NAD+ precursor supplementation improves tissue repair and metabolic health, the mitochondrial NAD+ liver regeneration regulatory mechanism at the subcellular level […]

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