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      December 05, 2025

      Transl Psychiatry: Early Life Stress + NAD+/SIRT1 Genetic Risk Drives Depression—A Cellular Energy Crisis

      For decades, depression has been unfairly dismissed as "overthinking" or "personal weakness." However, a groundbreaking study published in Transl Psychiatry reshapes this narrative...

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      November 28, 2025

      Nature Aging: NAD⁺ Metabolic Checkpoint—A Key Target to Reverse Hematopoietic Stem Cell Aging

      With advancing age, the function of hematopoietic stem cells (HSCs)—the "seed cells" of the blood system—gradually declines, a phenomenon known as "HSC aging." This dec...

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      November 21, 2025

      Cell Study Identifies SARM1 as a DNA-Damage Sensor Driving NAD⁺ Depletion — A Mechanism with Implications for Aging and Cellular Resilience

      A new study from Dalian Medical University, published in Cell, provides the clearest evidence to date that SARM1 acts as a direct DNA-damage sensor. When activated by abnormal double-stranded DNA (dsD...

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  • September 13, 2023
    Newly confirmed biochemical mechanism in cells is key component of the anti-aging program

    Ageing is an inevitable part of life, yet some species are ageing very differently than others, even...

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  • July 25, 2022
    Why NAD+ Declines During Aging

    This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the prev...

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  • July 08, 2022
    Taking NAD+ to the next level

    A new player in the NAD+ supplement market has arrived on the scene, in the shape of Nuchido, a UK-b...

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  • November 13, 2024
    Gene-editing discovery could point cures for mitochondrial diseases

    Biologist David Liu was in the middle of his morning commute to the Broad Institute two summers ago ...

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  • August 13, 2022
    Age-Related Female Fertility Decline Linked to Mitochondrial Mutation

    According to new research, mutations accumulate in the mitochondrial DNA of egg cells, leading to ch...

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  • May 30, 2022
    Is Aging a Disease You Can Reverse?

    DAVE ASPREY, founder of the supplement company Bulletproof and one of the many Silicon Valley tech t...

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About
Company
Reserch Recruitment
Contact
Careers
Platform
Aging mechanism research
AI Network pharmacology
TURN A drug delivery
Products evaluation and Clinical Research
Pipeline
Shop
News
Research
Publications
Celfavor™ NADH
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